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Accuracy of heritability estimations in presence of hidden population stratification

The heritability of a trait is the proportion of its variance explained by genetic factors; it has historically been estimated using familial data. However, new methods have appeared for estimating heritabilities using genomewide data from unrelated individuals. A drawback of this strategy is that p...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Dandine-Roulland, Claire, Bellenguez, Céline, Debette, Stéphanie, Amouyel, Philippe, Génin, Emmanuelle, Perdry, Hervé
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879529/
https://ncbi.nlm.nih.gov/pubmed/27220488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26471
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