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On Negative Heritability and Negative Estimates of Heritability

We consider the problem of interpreting negative maximum likelihood estimates of heritability that sometimes arise from popular statistical models of additive genetic variation. These may result from random noise acting on estimates of genuinely positive heritability, but we argue that they may also...

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Veröffentlicht in:Genetics
Hauptverfasser: Steinsaltz, David, Dahl, Andy, Wachter, Kenneth W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268991/
https://ncbi.nlm.nih.gov/pubmed/32291292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303161
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