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Where is the causal variant? On the advantage of the family design over the case–control design in genetic association studies
Many associated single-nucleotide polymorphisms (SNPs) have been identified by association studies for numerous diseases. However, the association between a SNP and a disease can result from a causal variant in linkage disequilibrium (LD) with the considered SNP. Assuming that the true causal varian...
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| Publicat a: | Eur J Hum Genet |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592080/ https://ncbi.nlm.nih.gov/pubmed/25585700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.284 |
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