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Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease

AIMS: Genetic factors do not seem to account fully for Alzheimer disease (AD) pathogenesis. There is evidence for the contribution of environmental factors, whose effect may be mediated by epigenetic mechanisms. Epigenetics involves the regulation of gene expression independently of DNA sequence and...

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Detalhes bibliográficos
Publicado no:Neuropathol Appl Neurobiol
Main Authors: Lashley, Tammaryn, Gami, Priya, Valizadeh, Navid, Li, Abi, Revesz, Tamas, Balazs, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879505/
https://ncbi.nlm.nih.gov/pubmed/25201696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12183
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