Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases

OBJECTIVES: Type 1 interferons (IFN-1) are implicated in the pathogenesis of systemic lupus erythematosus (SLE), but most studies have only reported the effect of IFN-1 on mixed cell populations. We aimed to define modules of IFN-1-associated genes in purified leucocyte populations and use these as...

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Publicado en:RMD Open
Autores principales: Flint, Shaun M, Jovanovic, Vojislav, Teo, Boon Wee, Mak, Anselm, Thumboo, Julian, McKinney, Eoin F, Lee, James C, MacAry, Paul, Kemeny, David M, Jayne, David RW, Fong, Kok Yong, Lyons, Paul A, Smith, Kenneth GC
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2016
Materias:
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879345/
https://ncbi.nlm.nih.gov/pubmed/27252891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2015-000183
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