Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases

OBJECTIVES: Type 1 interferons (IFN-1) are implicated in the pathogenesis of systemic lupus erythematosus (SLE), but most studies have only reported the effect of IFN-1 on mixed cell populations. We aimed to define modules of IFN-1-associated genes in purified leucocyte populations and use these as...

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Detalhes bibliográficos
Publicado no:RMD Open
Main Authors: Flint, Shaun M, Jovanovic, Vojislav, Teo, Boon Wee, Mak, Anselm, Thumboo, Julian, McKinney, Eoin F, Lee, James C, MacAry, Paul, Kemeny, David M, Jayne, David RW, Fong, Kok Yong, Lyons, Paul A, Smith, Kenneth GC
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
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Lupus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879345/
https://ncbi.nlm.nih.gov/pubmed/27252891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2015-000183
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