Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases

OBJECTIVES: Type 1 interferons (IFN-1) are implicated in the pathogenesis of systemic lupus erythematosus (SLE), but most studies have only reported the effect of IFN-1 on mixed cell populations. We aimed to define modules of IFN-1-associated genes in purified leucocyte populations and use these as...

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Veröffentlicht in:RMD Open
Hauptverfasser: Flint, Shaun M, Jovanovic, Vojislav, Teo, Boon Wee, Mak, Anselm, Thumboo, Julian, McKinney, Eoin F, Lee, James C, MacAry, Paul, Kemeny, David M, Jayne, David RW, Fong, Kok Yong, Lyons, Paul A, Smith, Kenneth GC
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879345/
https://ncbi.nlm.nih.gov/pubmed/27252891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2015-000183
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