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Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers
Tonic inhibition was imaged in cerebellar granule cells of transgenic mice expressing the optogenetic chloride indicator, Clomeleon. Blockade of GABA(A) receptors substantially reduced chloride concentration in granule cells due to block of tonic inhibition. This indicates that tonic inhibition is a...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879193/ https://ncbi.nlm.nih.gov/pubmed/27225762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4366-15.2016 |
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