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Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers

Tonic inhibition was imaged in cerebellar granule cells of transgenic mice expressing the optogenetic chloride indicator, Clomeleon. Blockade of GABA(A) receptors substantially reduced chloride concentration in granule cells due to block of tonic inhibition. This indicates that tonic inhibition is a...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Berglund, Ken, Wen, Lei, Dunbar, Robert L., Feng, Guoping, Augustine, George J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879193/
https://ncbi.nlm.nih.gov/pubmed/27225762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4366-15.2016
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