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Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers

Tonic inhibition was imaged in cerebellar granule cells of transgenic mice expressing the optogenetic chloride indicator, Clomeleon. Blockade of GABA(A) receptors substantially reduced chloride concentration in granule cells due to block of tonic inhibition. This indicates that tonic inhibition is a...

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Опубликовано в: :J Neurosci
Главные авторы: Berglund, Ken, Wen, Lei, Dunbar, Robert L., Feng, Guoping, Augustine, George J.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879193/
https://ncbi.nlm.nih.gov/pubmed/27225762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4366-15.2016
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