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Increased diet-induced fatty streak formation in female mice with deficiency of liver-derived insulin-like growth factor-I
The role of endocrine IGF-I for atherosclerosis is unclear. We determined the importance of circulating, liver-derived IGF-I for fatty streak formation in mice. Mice with adult, liver-specific IGF-I inactivation (LI-IGF-I(−/−) mice, serum IGF-I reduced by approximately 80 %) and control mice receive...
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| Udgivet i: | Endocrine |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879167/ https://ncbi.nlm.nih.gov/pubmed/26627099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-015-0809-1 |
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