The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice

Androgens have important cardiometabolic actions in males, but their metabolic role in females is unclear. To determine the physiologic androgen receptor (AR)–dependent actions of androgens on atherogenesis in female mice, we generated female AR-knockout (ARKO) mice on an atherosclerosis-prone apoli...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Fagman, Johan B., Wilhelmson, Anna S., Motta, Benedetta M., Pirazzi, Carlo, Alexanderson, Camilla, De Gendt, Karel, Verhoeven, Guido, Holmäng, Agneta, Anesten, Fredrik, Jansson, John-Olov, Levin, Malin, Borén, Jan, Ohlsson, Claes, Krettek, Alexandra, Romeo, Stefano, Tivesten, Åsa
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470404/
https://ncbi.nlm.nih.gov/pubmed/25550469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259234
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