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Computational Study of Rh-Catalyzed Carboacylation of Olefins: Ligand-Promoted Rhodacycle Isomerization Enables Regioselective C–C Bond Functionalization of Benzocyclobutenones

The mechanism, reactivity, regio- and enantioselectivity of the Rh-catalyzed carboacylation of benzocyclobutenones are investigated using density functional theory (DFT) calculations. The calculations indicate that the selective activation of the relatively unreactive C1–C2 bond in benzocyclobutenon...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lu, Gang, Fang, Cheng, Xu, Tao, Dong, Guangbin, Liu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878673/
https://ncbi.nlm.nih.gov/pubmed/26051406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04691
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