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Lateral adhesion drives reintegration of misplaced cells into epithelial monolayers

Cells in simple epithelia orient their mitotic spindles in the plane of the epithelium so that both daughter cells are born within the epithelial sheet. This is assumed to be important to maintain epithelial integrity and prevent hyperplasia, because misaligned divisions give rise to cells outside t...

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Publicado en:Nat Cell Biol
Autores principales: Bergstralh, Dan T., Lovegrove, Holly E., St Johnston, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878657/
https://ncbi.nlm.nih.gov/pubmed/26414404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3248
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