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Lateral adhesion drives reintegration of misplaced cells into epithelial monolayers
Cells in simple epithelia orient their mitotic spindles in the plane of the epithelium so that both daughter cells are born within the epithelial sheet. This is assumed to be important to maintain epithelial integrity and prevent hyperplasia, because misaligned divisions give rise to cells outside t...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878657/ https://ncbi.nlm.nih.gov/pubmed/26414404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3248 |
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