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Lateral adhesion drives reintegration of misplaced cells into epithelial monolayers

Cells in simple epithelia orient their mitotic spindles in the plane of the epithelium so that both daughter cells are born within the epithelial sheet. This is assumed to be important to maintain epithelial integrity and prevent hyperplasia, because misaligned divisions give rise to cells outside t...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Bergstralh, Dan T., Lovegrove, Holly E., St Johnston, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878657/
https://ncbi.nlm.nih.gov/pubmed/26414404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3248
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