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Discs Large Links Spindle Orientation to Apical-Basal Polarity in Drosophila Epithelia

Mitotic spindles in epithelial cells are oriented in the plane of the epithelium so that both daughter cells remain within the monolayer, and defects in spindle orientation have been proposed to promote tumorigenesis by causing epithelial disorganization and hyperplasia [1]. Previous work has implic...

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Hlavní autoři: Bergstralh, Dan T., Lovegrove, Holly E., St Johnston, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770898/
https://ncbi.nlm.nih.gov/pubmed/23891112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.07.017
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