GDNF is not required for catecholaminergic neuron survival in vivo

Glial cell line-derived neurotrophic factor (GDNF) has been tested in clinical trials to treat Parkinson’s disease with promising but variable results. Improvement of therapeutic effectiveness requires solid understanding of the physiological role of GDNF in the maintenance of the adult brain catech...

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Udgivet i:Nat Neurosci
Main Authors: Kopra, Jaakko, Vilenius, Carolina, Grealish, Shane, Härma, Mari-Anne, Varendi, Kärt, Lindholm, Jesse, Castrén, Eero, Võikar, Vootele, Björklund, Anders, Piepponen, T. Petteri, Saarma, Mart, Andressoo, Jaan-Olle
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878654/
https://ncbi.nlm.nih.gov/pubmed/25710828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3941
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