DNase I aggravates islet β-cell apoptosis in type 2 diabetes

Deoxyribonuclease I (DNase I) is an endonuclease responsible for the destruction of chromatin during apoptosis. However, its role in diabetes remains unclear. The aim of the current study was to investigate the role of DNase I combined with high glucose levels in β-cell apoptosis. Human samples were...

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Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: ZHU, BIN, ZHANG, LEI, ZHANG, YUE-YING, WANG, LEI, LI, XIN-GANG, LIU, TENG, FU, YU-KE, ZHENG, YAN-FEI, LI, PING, ZHAO, ZHI-GANG
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878546/
https://ncbi.nlm.nih.gov/pubmed/27082840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5102
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