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DNase I aggravates islet β-cell apoptosis in type 2 diabetes

Deoxyribonuclease I (DNase I) is an endonuclease responsible for the destruction of chromatin during apoptosis. However, its role in diabetes remains unclear. The aim of the current study was to investigate the role of DNase I combined with high glucose levels in β-cell apoptosis. Human samples were...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: ZHU, BIN, ZHANG, LEI, ZHANG, YUE-YING, WANG, LEI, LI, XIN-GANG, LIU, TENG, FU, YU-KE, ZHENG, YAN-FEI, LI, PING, ZHAO, ZHI-GANG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878546/
https://ncbi.nlm.nih.gov/pubmed/27082840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5102
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