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DNase I aggravates islet β-cell apoptosis in type 2 diabetes

Deoxyribonuclease I (DNase I) is an endonuclease responsible for the destruction of chromatin during apoptosis. However, its role in diabetes remains unclear. The aim of the current study was to investigate the role of DNase I combined with high glucose levels in β-cell apoptosis. Human samples were...

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Publicat a:Mol Med Rep
Autors principals: ZHU, BIN, ZHANG, LEI, ZHANG, YUE-YING, WANG, LEI, LI, XIN-GANG, LIU, TENG, FU, YU-KE, ZHENG, YAN-FEI, LI, PING, ZHAO, ZHI-GANG
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878546/
https://ncbi.nlm.nih.gov/pubmed/27082840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5102
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