Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.

2-Chlorodeoxyadenosine (CdA) is active in chronic lymphocytic leukemia, hairy-cell leukemia, and low-grade lymphomas. In part, this spectrum of activity may be attributable to the selective toxicity of CdA to nondividing lymphocytes and monocytes. However, CdA is unstable at acidic pH and is degrade...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Carson, D A, Wasson, D B, Esparza, L M, Carrera, C J, Kipps, T J, Cottam, H B
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1992
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1348362/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2970
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