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Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans
In Caenorhabditis elegans, removing germ cells slows aging and extends life. Here we show that transcription factors that extend life and confer protection to age-related protein-aggregation toxicity are activated early in adulthood in response to a burst of reactive oxygen species (ROS) and a shift...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878494/ https://ncbi.nlm.nih.gov/pubmed/27140632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524727113 |
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