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Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans

In Caenorhabditis elegans, removing germ cells slows aging and extends life. Here we show that transcription factors that extend life and confer protection to age-related protein-aggregation toxicity are activated early in adulthood in response to a burst of reactive oxygen species (ROS) and a shift...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wei, Yuehua, Kenyon, Cynthia
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878494/
https://ncbi.nlm.nih.gov/pubmed/27140632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524727113
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