Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits

Electron tomography is an increasingly powerful method to study the detailed architecture of macromolecular complexes or cellular structures. Applied to amyloid deposits formed in a cell culture model of systemic amyloid A amyloidosis, we could determine the structural morphology of the fibrils dire...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kollmer, Marius, Meinhardt, Katrin, Haupt, Christian, Liberta, Falk, Wulff, Melanie, Linder, Julia, Handl, Lisa, Heinrich, Liesa, Loos, Cornelia, Schmidt, Matthias, Syrovets, Tatiana, Simmet, Thomas, Westermark, Per, Westermark, Gunilla T., Horn, Uwe, Schmidt, Volker, Walther, Paul, Fändrich, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878484/
https://ncbi.nlm.nih.gov/pubmed/27140609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523496113
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