Iodonium Ylide Mediated Radiofluorination of (18)F-FPEB and Validation for Human Use

Translation of new methodologies for labeling non-activated aromatic molecules with fluorine-18 remains a challenge. Here, we report a one-step, regioselective, metal-free (18)F-labeling method that employs a hypervalent iodonium(III) ylide precursor, to prepare the radiopharmaceutical (18)F-FPEB. M...

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Bibliografske podrobnosti
izdano v:J Nucl Med
Main Authors: Stephenson, Nickeisha A., Holland, Jason P., Kassenbrock, Alina, Yokell, Daniel L., Livni, Eli, Liang, Steven H., Vasdev, Neil
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878451/
https://ncbi.nlm.nih.gov/pubmed/25655630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.151332
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