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Mechanistic studies and radiofluorination of structurally diverse pharmaceuticals with spirocyclic iodonium(iii) ylides
Synthesis of non-activated electron-rich and sterically hindered (18)F-arenes remains a major challenge due to limitations of existing radiofluorination methodologies. Herein, we report on our mechanistic investigations of spirocyclic iodonium(iii) ylide precursors for arene radiofluorination, inclu...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987086/ https://ncbi.nlm.nih.gov/pubmed/27540460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00197a |
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