Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice

Macrophage inflammation marks all stages of atherogenesis, and AMPK is a regulator of macrophage inflammation. We therefore generated myeloid α1AMPK knockout (MAKO) mice on the LDL receptor knockout (LDLRKO) background to investigate whether myeloid deletion of α1AMPK exacerbates atherosclerosis. Wh...

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Bibliographic Details
Published in:Diabetes
Main Authors: Cao, Qiang, Cui, Xin, Wu, Rui, Zha, Lin, Wang, Xianfeng, Parks, John S., Yu, Liqing, Shi, Hang, Xue, Bingzhong
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2016
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878417/
https://ncbi.nlm.nih.gov/pubmed/26822081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0917
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