Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology

The risk of type 2 diabetes (T2D) is increased by abnormalities in sleep quantity and quality, circadian alignment, and melatonin regulation. A common genetic variant in a receptor for the circadian-regulated hormone melatonin (MTNR1B) is associated with increased fasting blood glucose and risk of T...

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Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Lane, Jacqueline M., Chang, Anne-Marie, Bjonnes, Andrew C., Aeschbach, Daniel, Anderson, Clare, Cade, Brian E., Cain, Sean W., Czeisler, Charles A., Gharib, Sina A., Gooley, Joshua J., Gottlieb, Daniel J., Grant, Struan F.A., Klerman, Elizabeth B., Lauderdale, Diane S., Lockley, Steven W., Munch, Miriam, Patel, Sanjay, Punjabi, Naresh M., Rajaratnam, Shanthakumar M.W., Rueger, Melanie, St. Hilaire, Melissa A., Santhi, Nayantara, Scheuermaier, Karin, Van Reen, Eliza, Zee, Phyllis C., Shea, Steven A., Duffy, Jeanne F., Buxton, Orfeu M., Redline, Susan, Scheer, Frank A.J.L., Saxena, Richa
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2016
Teme:
Genetics/Genomes/Proteomics/Metabolomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878414/
https://ncbi.nlm.nih.gov/pubmed/26868293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0999
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