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Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression

Neurogenin-3 (ngn-3) expression is critical for endocrine development in the developing pancreas. We found that when ngn-3 was inhibited in an E11.5 pancreas, using either morpholino antisense or siRNA, it led to a significant decrease in endocrine differentiation after seven days in culture. Endocr...

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Bibliografiska uppgifter
I publikationen:Biochem Biophys Res Commun
Huvudupphovsmän: Prasadan, Krishna, Tulachan, Sidhartha, Guo, Ping, Shiota, Chiyo, Shah, Sohail, Gittes, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878388/
https://ncbi.nlm.nih.gov/pubmed/20471370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.058
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