The R18 Polyarginine Peptide Is More Effective Than the TAT-NR2B9c (NA-1) Peptide When Administered 60 Minutes after Permanent Middle Cerebral Artery Occlusion in the Rat

We examined the dose responsiveness of polyarginine R18 (100, 300, and 1000 nmol/kg) when administered 60 minutes after permanent middle cerebral artery occlusion (MCAO). The TAT-NR2B9c peptide, which is known to be neuroprotective in rodent and nonhuman primate stroke models, served as a positive c...

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Publicat a:Stroke Res Treat
Autors principals: Milani, D., Knuckey, N. W., Anderton, R. S., Cross, J. L., Meloni, B. P.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877491/
https://ncbi.nlm.nih.gov/pubmed/27247825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2372710
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