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Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
BACKGROUND: The search for intrinsic factors, which account for a protein's capability to act as an allergen, is ongoing. Fold stability has been identified as a molecular feature that affects processing and presentation, thereby influencing an antigen's immunologic properties. OBJECTIVE:...
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Pubblicato in: | J Allergy Clin Immunol |
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Autori principali: | , , , , , , , , , , , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Mosby
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877439/ https://ncbi.nlm.nih.gov/pubmed/26559323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.09.026 |
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