Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells

Epidermal growth factor receptor (EGFR) signaling has a critical role in oncogenic Kras-driven pancreatic carcinogenesis. However, the downstream targets of this signaling network are largely unknown. We developed a novel model system utilizing murine primary pancreatic ductal epithelial cells (PDEC...

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Publicado en:Oncogene
Autores principales: Diersch, Sandra, Wirth, Matthias, Schneeweis, Christian, Jörs, Simone, Geisler, Fabian, Siveke, Jens T., Rad, Roland, Schmid, Roland M., Saur, Dieter, Rustgi, Anil K., Reichert, Maximilian, Schneider, Günter
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877299/
https://ncbi.nlm.nih.gov/pubmed/26592448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.437
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