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Spotlight on idarucizumab and its potential for the reversal of anticoagulant effects of dabigatran

Idarucizumab is the first targeted antidote of dabigatran, a direct oral anticoagulant used for prevention and treatment of venous thromboembolism and prevention of stroke in atrial fibrillation. Idarucizumab is a humanized fragment of a monoclonal antibody, which binds dabigatran reversibly with hi...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autore principale: Sié, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876800/
https://ncbi.nlm.nih.gov/pubmed/27274201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S94167
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