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Spotlight on idarucizumab and its potential for the reversal of anticoagulant effects of dabigatran

Idarucizumab is the first targeted antidote of dabigatran, a direct oral anticoagulant used for prevention and treatment of venous thromboembolism and prevention of stroke in atrial fibrillation. Idarucizumab is a humanized fragment of a monoclonal antibody, which binds dabigatran reversibly with hi...

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Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Glavni avtor: Sié, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876800/
https://ncbi.nlm.nih.gov/pubmed/27274201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S94167
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