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Long-term effect of ropivacaine nanoparticles for sciatic nerve block on postoperative pain in rats

PURPOSE: The analgesic effect of ropivacaine (Rop) for nerve block lasts only ~3–6 hours for single use. The aim of this study was to develop long-acting regional anesthetic Rop nanoparticles and investigate the effects of sciatic nerve block on postoperative pain in rats. MATERIALS AND METHODS: Rop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Wang, Zi, Huang, Haizhen, Yang, Shaozhong, Huang, Shanshan, Guo, Jingxuan, Tang, Qi, Qi, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876796/
https://ncbi.nlm.nih.gov/pubmed/27274236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S101563
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