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Effects of local dexmedetomidine administration on the neurotoxicity of ropivacaine for sciatic nerve block in rats

Dexmedetomidine, used as an adjuvant to local anesthetics (LAs), may prolong the duration of peripheral nerve block. However, the effect of dexmedetomidine on the neurotoxicity of LAs is not completely understood. The present study was designed to investigate the efficacy of two doses of dexmedetomi...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Xue, Xing, Fan, Jun, Ma, Xiaoli, Liu, Yongqiang, Han, Xuena, Leng, Yufang, Yu, Jinjia
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533505/
https://ncbi.nlm.nih.gov/pubmed/33000208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11514
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