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Long-term effect of ropivacaine nanoparticles for sciatic nerve block on postoperative pain in rats

PURPOSE: The analgesic effect of ropivacaine (Rop) for nerve block lasts only ~3–6 hours for single use. The aim of this study was to develop long-acting regional anesthetic Rop nanoparticles and investigate the effects of sciatic nerve block on postoperative pain in rats. MATERIALS AND METHODS: Rop...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wang, Zi, Huang, Haizhen, Yang, Shaozhong, Huang, Shanshan, Guo, Jingxuan, Tang, Qi, Qi, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876796/
https://ncbi.nlm.nih.gov/pubmed/27274236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S101563
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