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The hemifusion structure induced by Influenza virus haemagglutinin is determined by physical properties of the target membranes

Influenza A virus hemagglutinin (HA) changes conformation and drives membrane fusion of viral and endosomal membrane at low pH. Membrane fusion proceeds through an intermediate called hemifusion(1,2). For viral fusion the hemifusion structures are not determined(3). Here, influenza virus-like partic...

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Bibliographic Details
Published in:Nat Microbiol
Main Authors: Chlanda, Petr, Mekhedov, Elena, Waters, Hang, Schwartz, Cindi L., Fischer, Elizabeth R., Ryham, Rolf J., Cohen, Fredric S., Blank, Paul S., Zimmerberg, Joshua
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876733/
https://ncbi.nlm.nih.gov/pubmed/27572837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.50
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