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Cholesterol Promotes Hemifusion and Pore Widening in Membrane Fusion Induced by Influenza Hemagglutinin

Cholesterol-specific interactions that affect membrane fusion were tested for using insect cells; cells that have naturally low cholesterol levels (<4 mol %). Sf9 cells were engineered (HAS cells) to express the hemagglutinin (HA) of the influenza virus X-31 strain. Enrichment of HAS cells with c...

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Main Authors: Biswas, Subrata, Yin, Shu-Rong, Blank, Paul S., Zimmerberg, Joshua
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346574/
https://ncbi.nlm.nih.gov/pubmed/18443361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709932
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