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The Pathway of Membrane Fusion Catalyzed by Influenza Hemagglutinin: Restriction of Lipids, Hemifusion, and Lipidic Fusion Pore Formation

The mechanism of bilayer unification in biological fusion is unclear. We reversibly arrested hemagglutinin (HA)-mediated cell–cell fusion right before fusion pore opening. A low-pH conformation of HA was required to form this intermediate and to ensure fusion beyond it. We present evidence indicatin...

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Bibliographische Detailangaben
Hauptverfasser: Chernomordik, Leonid V., Frolov, Vadim A., Leikina, Eugenia, Bronk, Peter, Zimmerberg, Joshua
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132678/
https://ncbi.nlm.nih.gov/pubmed/9508770
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