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An Efficient Nonlinear Regression Approach for Genome-wide Detection of Marginal and Interacting Genetic Variations

Genome-wide association studies have revealed individual genetic variants associated with phenotypic traits such as disease risk and gene expressions. However, detecting pairwise interaction effects of genetic variants on traits still remains a challenge due to a large number of combinations of vari...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Lee, Seunghak, Lozano, Aurélie, Kambadur, Prabhanjan, Xing, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876555/
https://ncbi.nlm.nih.gov/pubmed/27159633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2015.0202
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