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Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue

Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are developmental disorders. No validated blood-based biomarkers exist for either, which impedes bench-to-bedside approaches. Amyloid-β (Aβ) precursor protein (APP) and metabolites are usually associated with Alzheimer’s disease (AD). APP c...

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Vydáno v:Sci Rep
Hlavní autoři: Ray, Balmiki, Sokol, Deborah K., Maloney, Bryan, Lahiri, Debomoy K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876513/
https://ncbi.nlm.nih.gov/pubmed/27212113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26052
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