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Safety, Tolerability and Pharmacokinetics of FAAH Inhibitor V158866: A Double-Blind, Randomised, Placebo-Controlled Phase I Study in Healthy Volunteers

BACKGROUND AND OBJECTIVE: The inhibition of fatty acid amide hydrolase 1 (FAAH) has been proposed as a novel mechanism for treating pain syndromes by increasing the levels of endogenous cannabinoids (ECs). This study describes the safety, tolerability, pharmacokinetics and pharmacodynamics of V15886...

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Detalhes bibliográficos
Publicado no:Drugs R D
Main Authors: Pawsey, Stephen, Wood, Mike, Browne, Helen, Donaldson, Kirsteen, Christie, Mark, Warrington, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875922/
https://ncbi.nlm.nih.gov/pubmed/26987975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-016-0127-y
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