Safety, Tolerability and Pharmacokinetics of FAAH Inhibitor V158866: A Double-Blind, Randomised, Placebo-Controlled Phase I Study in Healthy Volunteers

Por Pawsey, Stephen, Wood, Mike, Browne, Helen, Donaldson, Kirsteen, Christie, Mark, Warrington, Steven
Publicado no Drugs R D (2016)

Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design

Por Massey, Andrew J., Stokes, Stephen, Browne, Helen, Foloppe, Nicolas, Fiumana, Andreá, Scrace, Simon, Fallowfield, Mandy, Bedford, Simon, Webb, Paul, Baker, Lisa, Christie, Mark, Drysdale, Martin J., Wood, Mike
Publicado no Oncotarget (2015)

VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells

Por Moore, Jonathan D., Staniszewska, Anna, Shaw, Terence, D'Alessandro, Jalanie, Davis, Ben, Surgenor, Alan, Baker, Lisa, Matassova, Natalia, Murray, James, Macias, Alba, Brough, Paul, Wood, Mike, Mahon, Patrick C.
Publicado no Oncotarget (2014)

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

Por Casara, Patrick, Davidson, James, Claperon, Audrey, Le Toumelin-Braizat, Gaëtane, Vogler, Meike, Bruno, Alain, Chanrion, Maïa, Lysiak-Auvity, Gaëlle, Le Diguarher, Thierry, Starck, Jérôme-Benoît, Chen, Ijen, Whitehead, Neil, Graham, Christopher, Matassova, Natalia, Dokurno, Pawel, Pedder, Christopher, Wang, Youzhen, Qiu, Shumei, Girard, Anne-Marie, Schneider, Emilie, Gravé, Fabienne, Studeny, Aurélie, Guasconi, Ghislaine, Rocchetti, Francesca, Maïga, Sophie, Henlin, Jean-Michel, Colland, Frédéric, Kraus-Berthier, Laurence, Le Gouill, Steven, Dyer, Martin J.S., Hubbard, Roderick, Wood, Mike, Amiot, Martine, Cohen, Gerald M, Hickman, John A., Morris, Erick, Murray, James, Geneste, Olivier
Publicado no Oncotarget (2018)