Double-blind, randomized, placebo-controlled study of safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-683, an investigational metastin analogue in healthy men

AIMS: Two randomized, double-blind, placebo-controlled studies were performed to characterize the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of the investigational metastin analogue, TAK-683, in healthy men. METHODS: We first investigated a single subcutaneous (s.c.) dose...

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Hlavní autoři: Scott, Graham, Ahmad, Irfan, Howard, Katy, MacLean, David, Oliva, Cristina, Warrington, Steve, Wilbraham, Darren, Worthington, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2013
Témata:
Clinical Trials
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579253/
https://ncbi.nlm.nih.gov/pubmed/22803642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04385.x
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