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Homeostatic PPARα signaling limits inflammatory responses to commensal microbiota in the intestine

Dietary lipids and their metabolites activate members of the peroxisome proliferative-activated receptor (PPAR) family of transcription factors and are critical for colonic health. The PPARα isoform plays a vital role in regulating inflammation in various disease settings, but its role in intestinal...

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Veröffentlicht in:J Immunol
Hauptverfasser: Manoharan, Indumathi, Suryawanshi, Amol, Hong, Yuan, Ranganathan, Punithavathi, Shanmugam, Arulkumaran, Ahmad, Shamim, Swafford, Daniel, Manicassamy, Balaji, Ramesh, Ganesan, Koni, Pandelakis A., Thangaraju, Muthusamy, Manicassamy, Santhakumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875842/
https://ncbi.nlm.nih.gov/pubmed/27183583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501489
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