Activation of chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712 by ethanol shock: insights from the promoter fusion studies

BACKGROUND: Streptomyces venezuelae ATCC 10712 produces antibiotics chloramphenicol (Cml) and jadomycin (Jad) in response to nutrient limitation and ethanol shock (ES), respectively. Biosynthesis of Cml and Jad was shown to be reciprocally regulated via the action of regulatory proteins JadR1 and Ja...

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Gepubliceerd in:Microb Cell Fact
Hoofdauteurs: Sekurova, Olga N., Zhang, Jianhai, Kristiansen, Kåre A., Zotchev, Sergey B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875748/
https://ncbi.nlm.nih.gov/pubmed/27206520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0484-9
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