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Activation of chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712 by ethanol shock: insights from the promoter fusion studies

BACKGROUND: Streptomyces venezuelae ATCC 10712 produces antibiotics chloramphenicol (Cml) and jadomycin (Jad) in response to nutrient limitation and ethanol shock (ES), respectively. Biosynthesis of Cml and Jad was shown to be reciprocally regulated via the action of regulatory proteins JadR1 and Ja...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Sekurova, Olga N., Zhang, Jianhai, Kristiansen, Kåre A., Zotchev, Sergey B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875748/
https://ncbi.nlm.nih.gov/pubmed/27206520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0484-9
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