Activation of chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712 by ethanol shock: insights from the promoter fusion studies

BACKGROUND: Streptomyces venezuelae ATCC 10712 produces antibiotics chloramphenicol (Cml) and jadomycin (Jad) in response to nutrient limitation and ethanol shock (ES), respectively. Biosynthesis of Cml and Jad was shown to be reciprocally regulated via the action of regulatory proteins JadR1 and Ja...

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Enregistré dans:
Détails bibliographiques
Publié dans:Microb Cell Fact
Auteurs principaux: Sekurova, Olga N., Zhang, Jianhai, Kristiansen, Kåre A., Zotchev, Sergey B.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875748/
https://ncbi.nlm.nih.gov/pubmed/27206520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0484-9
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