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Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics
SIRT6 is an important histone modifying protein that regulates DNA repair, telomere maintenance, energy metabolism, and target gene expression. Recently SIRT6 has been identified as a tumor suppressor and is down-regulated in certain cancer types, but not in other cancers. From deposited gene profil...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875531/ https://ncbi.nlm.nih.gov/pubmed/23982738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-3054-5 |
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