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Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics
SIRT6 is an important histone modifying protein that regulates DNA repair, telomere maintenance, energy metabolism, and target gene expression. Recently SIRT6 has been identified as a tumor suppressor and is down-regulated in certain cancer types, but not in other cancers. From deposited gene profil...
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| 出版年: | Protein Cell |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Higher Education Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875531/ https://ncbi.nlm.nih.gov/pubmed/23982738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-3054-5 |
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