LAT-1 Activity of meta-Substituted Phenylalanine and Tyrosine Analogs

The transporter protein Large-neutral Amino Acid Transporter 1 (LAT-1, SLC7A5) is responsible for transporting amino acids such as tyrosine and phenylalanine as well as thyroid hormones, and it has been exploited as a drug delivery mechanism. Recently its role in cancer has become increasingly appre...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Augustyn, Evan, Finke, Karissa, Zur, Arik A., Hansen, Logan, Heeren, Nathan, Chien, Huan-Chieh, Lin, Lawrence, Giacomini, Kathleen M., Colas, Claire, Schlessinger, Avner, Thomas, Allen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875506/
https://ncbi.nlm.nih.gov/pubmed/27106710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.04.023
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