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Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses

The Rad1 gene is evolutionarily conserved from yeast to human. The fission yeast Schizosaccharomyces pombe Rad1 ortholog promotes cell survival against DNA damage and is required for G(2)/M checkpoint activation. In this study, mouse embryonic stem (ES) cells with a targeted deletion of Mrad1, the m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Protein Cell
Egile Nagusiak: Zhang, Chunbo, Liu, Yuheng, Hu, Zhishang, An, Lili, He, Yikun, Hang, Haiying
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Higher Education Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875338/
https://ncbi.nlm.nih.gov/pubmed/21637962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1049-7
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